Abstract — The recent rapid growth in demand for aesthe tic non - invasive l aser treatments such as unwanted skin rejuvena tion, removal of age - related vascular blemishes has led to a boom in the medical devices to treat these conditions. Among diverse laser for skin treatment, c opper bromide laser is a very effective, safe, and well tolerated treatmen t for facial telangiectasia at various energy levels and the most important thing of the copper bromide laser device is that the stability of the energy . However there is no evidence about effective copper bromide laser ’ s energy level for the treatment of vascular lesions . We compared energy stability and treat ment performance between two energy levels in 2W and 8W which commonly use in laser treatment for the vascular lesions . 8W copper bromide laser was more stable compare d than 2W copper bromide laser. A lso, 8W copper bromide laser was effectively superior to 2W copper bromide laser in treatment of vascular legion. Consequently , 8W copper bromide laser treatment for vascular lesion might be more suitable than 2W copper bromide laser.
I. I NTRODUCTION The yel low laser is known to affect epidermis melanin, vessel structures of degenerated corium, and epidermal VEGF while showing antiangiogenic effects which are thought to aid freckle treatment. According to a recent clinical research, the manifestation of VEGF within keratogenesis cells significantly diminished after copper bromide yellow laser (578nm) treatment, as the yellow laser affects the formation of VEGF and corium vessels within keratogenesis cells, while inflammation vehicles directly and indirectly af fect the formation of melanin, effectively treating freckles. C opper bromide laser is a very effective, safe, and well tolerated treatment for facial telangiectasia at various energy levels. (1) Also, t he potential application of an antiangiogenetic copper bromide laser for the treatment of melasma specially accompanied by pronounced telangiectasia in Asian skin is a possible treatment option. (2) B ut, t he copper bromide laser is less suited to treating very small vessel lesions such as diffuse erythema, an d conversely very large vessels as well as those of the nasal alae. (3) Generally, copper bromide laser was an effective tool in the treatment of certain cutaneous vascular lesions. (4) And a 578 nm copper bromide (CuBr) yellow light laser produces excelle nt results in eradicating red telangiectases of the lower extremities that are less than 2 mm in diameter.
However, there are various energy levels for laser therapies . A rgon laser (0.5 watt, 5 to 7 minutes exposure) fused specimens had no evidence of suture material at the anastomotic line, and healing consisted of a bond between artery and vein wall tissues. ( 6 ) And a t 1 W, the tissue was desiccated and the welds disrupted when exposed to blood flow , but a t 0.50 W, the fusion failed after only minimal exposure to the laser energy because of tissue drying and retraction with temperatures . ( 7 ) Nd:YAG laser 1320 nm (2 Watt, 20 seconds and 3 Watt, 8 seconds) via an applicator with radial symmetrical light distribution occlusion of recto urogenital fistulae will be easier to achieve since fistula occlusion. (8 ) Carbonization of the metallic tip and adherence of atherosclerotic debris with secondary vessel tearing which pulses of 6 watts were delivered to the laser probe were potential adverse effects of the laser probe. ( 9 ) Laser with energy power of 8 - 10 watt irradiation a connective tissue scar was formed substituting the defect in the vascular wall and covered from the lumen side with a thin continuous layer of endothelium. ( 10 ) Radial heating by the hot t ip probe using a rgon laser with power of 10 watts can cause thermal perforation. Blood flow or saline infusion modifies nontarget heating and may offer significant protection to the vasculature. (1 1 ) P atients who underwent 15 watt laser angioplasty alone, no noticeable improvement in distal blood flow were demonstrated by doppler velocimetry, and reocclusion occurred either soon afterwards or later. (1 2 ) The Coronary laser balloon angioplasty system which consists of a 50 watt continuous wave laser has been shown to be effective in the management of acute failure of pressure to thermally weld tissue during coronary angioplasty.
T he data (la ser output energy) concerning the normal distribution and homogeneity of variance are shown in Table 1. Total 606 data from the copper bromide laser output energy was analyzed in 2W and 8W respectively. Both energy level were not satisfied with the require ments of normal distribution but data distribution from 8W energy level was close with normal distribution(p=0.01) than 2W energy level and their p value were(p<0.001). Also their data variance from copper bromide energy output level were significant diffe rent (P<0.001) surgical fibers
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